Can Ehlers Danlos Syndrome cause weight gain?

No, EDS can never cause weight. In fact, people having EDS lack muscle tone, especially those having hEDS, and they don’t have a lot of muscle tone at the waistline.

Their legs are fine because they are able to walk a lot at home or work, but above their waistline, they are extraordinarily skinny and can’t lift much. Affected people with EDS are always surprised by these symptoms, but EDS can affect the organs, especially the bladder and bowel movements. Some people with EDS need a feeding tube because they have trouble gaining weight.

What Causes Ehlers-Danlos Syndrome? And why the EDS patient cant gain weight?
EDS is believed to be caused by a gene mutation that affects collagen, which gives connective tissue its structure and power. Some of the genes linked to EDS provide instructions for producing collagen, while others regulate its functions. The connective tissue in the body’s skin, bones, blood vessels, and organs may become weaker due to mutations in any genes that affect collagen development or use. Some forms of EDS can be passed on from one generation to the next (known as “heritable”), whereas a chance gene mutation causes others during early development.

A few of the newly identified forms of EDS are linked to genes that don’t appear to be involved in collagen development at all, and we don’t yet know how their mutations result in EDS-like symptoms. Ehlers-Danlos Syndrome is characterized by repeated joint dislocations and chronic musculoskeletal pain. Individuals with this condition also have soft, extra-stretchy skin that bruises easily and poor muscle tone. The brain and spine are affected by some instances of Ehlers-Danlos Syndrome. Many of the issues associated with EDS are progressive, which means they worsen over time.


If people having EDS attempt to lift weights and work on their muscles, there are more chances of dislocating a joint or sublux. Due to this, they are unable to uphold much muscle mass there. While generalized joint hypermobility and tissue fragility have been identified as core features, recent research has revealed that EDS-HT is multisystemic, presenting with a broad range of articular and extra-articular symptoms. Among those affected, gastrointestinal issues, temporomandibular disorders, and anomalies of smell and taste are typical, all of which have severe consequences for feeding.

EDS form which affects most in gaining weight

Kyphoscoliosis is a form of EDS. This form of Ehlers-Danlos Syndrome is marked by extreme, progressive spinal curvature. It gets worse over time and can make breathing difficult by limiting lung expansion and effect gaining weight

Skeletal anomalies such as abnormally curved (bowed) limbs and short stature are associated with the spondylodysplastic EDS type.

In addition to the characteristic delicate, loose skin and poor muscle tone, infants with arthrochalasia EDS have extreme joint hypermobility and congenital hip dislocation.

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